SCHEMBL14226992

SCHEMBL14226992

Cn1c(=O)n(C)c(=O)n(CCCC(C)(C)C)c1=O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 8/20 0.36
RGS4 P49798 3/20 0.34
HTT P42858 1/20 0.34
DAO P14920 1/20 0.32
LMNA P02545 1/20 0.32
CCR6 P51684 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RGS8 P57771 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12997397 0.89 RGS4 (0.37) GRM2RGS4DAORGS8
SCHEMBL19493726 0.83 RGS4 (0.44) RGS4LMNACCR6L3MBTL1RGS8
SCHEMBL15984388 0.80 RGS4 (0.35) RGS4HTTDAOLMNASMN1; SMN2
SCHEMBL12997387 0.79 RGS4 (0.33) RGS4DAO
SCHEMBL16938090 0.79 DAO (0.39) GRM2RGS4HTTDAO
SCHEMBL19493727 0.77 CYP3A4 (0.50) L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL25867919 0.75 RGS4 (0.43) RGS4RGS8
SCHEMBL14226996 0.75 CYP3A4 (0.57) L3MBTL1SMN1; SMN2CYP1A2
SCHEMBL13223313 0.75 RGS4 (0.52) RGS4L3MBTL1RGS8CYP1A2CYP2C19
SCHEMBL22152939 0.74 DAO (0.42) GRM2RGS4DAORGS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023588-B2 Resist underlayer film forming composition containing silicon having nitrogen-containing ring NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-05-05 US disclosed
US-20120315765-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING NITROGEN-CONTAINING RING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120315765-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING NITROGEN-CONTAINING RING SRSF1, SRSF7, SRRM2 GRM2 3256/4885RGS4 2843/4885HTT 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.