SCHEMBL25867919

SCHEMBL25867919

CCCCCn1c(=O)n(CCCCC(C)(C)C)c(=O)n(CCCCC(C)(C)C)c1=O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RGS4 P49798 4/20 0.43
CNR2 P34972 8/20 0.41
ADORA2B P29275 1/20 0.41
PTGS1 P23219 3/20 0.38
PTGS2 P35354 3/20 0.38
MGLL Q99685 3/20 0.38
FAAH O00519 2/20 0.38
RGS8 P57771 2/20 0.38
GSK3B P49841 1/20 0.38
TNF P01375 1/20 0.37
MAPK10 P53779 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19336853 0.98 ADORA2B (0.43) RGS4CNR2ADORA2BPTGS1PTGS2
SCHEMBL19493726 0.91 RGS4 (0.44) RGS4CNR2RGS8GSK3BTNF
SCHEMBL15984388 0.90 RGS4 (0.35) RGS4CNR2ADORA2BMGLLFAAH
SCHEMBL20724125 0.88 RGS4 (0.45) RGS4CNR2ADORA2BRGS8GSK3B
SCHEMBL12997397 0.85 RGS4 (0.37) RGS4CNR2RGS8GSK3B
SCHEMBL6239660 0.85 RGS4 (0.50) RGS4CNR2ADORA2BPTGS1PTGS2
SCHEMBL19493532 0.83 RGS4 (0.37) RGS4CNR2ADORA2BGSK3B
SCHEMBL11840543 0.83 MGLL (0.52) RGS4CNR2ADORA2BPTGS1PTGS2
SCHEMBL4963710 0.83 MGLL (0.52) RGS4CNR2ADORA2BPTGS1PTGS2
SCHEMBL9626274 0.83 MGLL (0.52) RGS4CNR2ADORA2BPTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230231142-A1 FUNCTIONALIZED CROSS-LINKED POLYMER NETWORKS, METHODS OF MAKING SAME, AND USES THEREOF CORNELL UNIVERSITY 2023-07-20 US disclosed