SCHEMBL14227804

SCHEMBL14227804

CCC1(C(=O)O)OC(OC2C(COS(=O)(=O)O)OC(OC3COC(OC4C(COS(=O)(=O)O)OC(OC)C(OS(=O)(=O)O)C4OC)[C@H](OCC(=O)O)C3OC)C(OS(=O)(=O)O)C2OS(=O)(=O)O)C(OC)C(OC)C1OC1OC(COS(=O)(=O)O)C(OCCOCCOCCOCCN)C(OC)C1OC

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SERPINC1 P01008 2/20 0.40
▸ CXCL10 P02778 1/20 0.33
▸ CXCL8 P10145 1/20 0.33
▸ CCL2 P13500 1/20 0.33
▸ CCL5 P13501 1/20 0.33
▸ CXCL12 P48061 1/20 0.33
▸ FGF1 P05230 2/20 0.33
▸ F2 P00734 1/20 0.31
▸ F10 P00742 4/20 0.30
▸ FGF2 P09038 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14227801 0.87 SERPINC1 (0.37) SERPINC1FGF1F10FGF2
SCHEMBL12458594 0.83 SERPINC1 (0.59) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL17521735 0.83 SERPINC1 (0.40) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL17902153 0.81 SERPINC1 (0.39) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL13873870 0.78 SERPINC1 (0.57) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL12799309 0.75 SERPINC1 (0.68) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL14959633 0.73 SERPINC1 (0.57) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL15896273 0.70 SERPINC1 (0.69) SERPINC1CXCL10CXCL8CCL2CCL5
SCHEMBL17521737 0.69 SERPINC1 (0.35) SERPINC1F10
SCHEMBL17521736 0.67 MDK (0.42) FGF1F2FGF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9259389-B2 Pharmaceutical oral dosage form containing a synthetic oligosaccharide ENDOTIS PHARMA (FR) 2016-02-16 — — US disclosed
US-20120316132-A1 PHARMACEUTICAL ORAL DOSAGE FORM CONTAINING A SYNTHETIC OLIGOSACCHARIDE CATALENT FRANCE BEINHEIM SA 2012-12-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316132-A1 PHARMACEUTICAL ORAL DOSAGE FORM CONTAINING A SYNTHETIC OLIGOSACCHARIDE LIPA, SORD, SI SERPINC1 919/4885CXCL10 3119/4885CXCL8 987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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