Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | SPR | P35270 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311783 | 0.78 | DYRK1A (1.00) | DYRK1ATYMPGSK3BBACE1ADORA2A | |
| Hydrochloric Acid SCHEMBL25394322 | 0.76 | DYRK1A (0.96) | DYRK1ATYMPGSK3BBACE1ADORA2A | |
| SCHEMBL28309711 | 0.74 | DYRK1A (0.62) | DYRK1ATYMPGSK3BBACE1ADORA2A | |
| SCHEMBL15693107 | 0.74 | DYRK1A (0.62) | DYRK1ATYMPGSK3BBACE1ADORA2A | |
| SCHEMBL7851729 | 0.74 | DYRK1A (0.62) | DYRK1AGAANPC1TYMPGSK3B | |
| SCHEMBL7014736 | 0.74 | DYRK1A (0.62) | DYRK1ATYMPGSK3BBACE1ADORA2A | |
| SCHEMBL311846 | 0.73 | ALDH1A1 (0.49) | DYRK1ANPC1ADORA2AADORA1SPR | |
| SCHEMBL7164003 | 0.72 | DYRK1A (0.60) | DYRK1ATYMPGSK3BBACE1ADORA2A | |
| SCHEMBL3821179 | 0.71 | KDM4E (0.64) | GAANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL29909366 | 0.71 | KDM4E (0.64) | GAANPC1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905778-A2 | Novel 2'-C-methyl nucleoside derivatives | Metabasis Therapeutics, Inc. (US) | 2008-04-02 | — | — | EP | disclosed |