Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199819 | 0.88 | MEN1 (0.60) | MEN1KMT2ASGMS2GAALRRK2 | |
| SCHEMBL4941693 | 0.82 | MEN1 (0.63) | MEN1KMT2ASGMS2LRRK2SMN1; SMN2 | |
| SCHEMBL10323195 | 0.80 | LRRK2 (0.80) | MEN1KMT2ASGMS2LRRK2PARP1 | |
| SCHEMBL19049633 | 0.77 | SMN1; SMN2 (0.61) | MEN1KMT2ASGMS2GAALRRK2 | |
| SCHEMBL1648383 | 0.77 | MEN1 (1.00) | MEN1KMT2ASGMS2GAALRRK2 | |
| SCHEMBL875474 | 0.76 | SGMS2 (1.00) | MEN1KMT2ASGMS2GAAALDH1A1 | |
| SCHEMBL1650152 | 0.75 | LRRK2 (0.77) | MEN1KMT2ASGMS2GAALRRK2 | |
| SCHEMBL24934209 | 0.73 | F2R (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23367850 | 0.73 | MEN1 (0.62) | MEN1KMT2AALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL11779160 | 0.73 | KMT2A (0.63) | MEN1KMT2ASGMS2LRRK2KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | MEN1 4301/4885KMT2A 2424/4885SGMS2 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.