Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP3 | Q9H4L4 | 6/20 | 0.60 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.60 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.60 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.60 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.60 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20735909 | 0.87 | SENP2 (0.60) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL2592899 | 0.85 | CYP2C9 (0.73) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL2592902 | 0.85 | CYP2C9 (0.73) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL12177917 | 0.84 | CYP2C9 (0.75) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11401043 | 0.84 | SENP3 (0.67) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL14997205 | 0.83 | SENP3 (0.55) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL15120312 | 0.83 | SENP2 (0.72) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11938158 | 0.82 | PHLPP2 (0.64) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL2594010 | 0.82 | SENP3 (0.83) | SENP3SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL12177950 | 0.82 | SENP2 (0.64) | SENP3SENP2SENP1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042806-A2 | STILBENEDISULFONIC ACID DERIVATIVES AS INHIBITORS OF RETROVIRAL INTEGRASE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-04-10 | — | — | WO | disclosed |