Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228939 | 0.92 | LTB4R2 (0.33) | TP53MEN1KMT2A | |
| SCHEMBL14228937 | 0.90 | TP53 (0.36) | TP53MEN1KMT2ARIPK1SLC9A1 | |
| SCHEMBL14229028 | 0.89 | PSEN1 (0.35) | TP53MEN1KMT2ARIPK1GAA | |
| SCHEMBL14543580 | 0.86 | TP53 (0.35) | TP53MEN1KMT2AGAA | |
| SCHEMBL14200501 | 0.85 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL14229219 | 0.85 | MEN1 (0.35) | TP53MEN1KMT2ARIPK1SLC9A1 | |
| SCHEMBL14229074 | 0.85 | CYP1A2 (0.36) | TP53MEN1KMT2A | |
| SCHEMBL14229693 | 0.85 | ALDH1A1 (0.45) | MEN1KMT2A | |
| SCHEMBL14230197 | 0.83 | MEN1 (0.33) | TP53MEN1KMT2A | |
| SCHEMBL14229433 | 0.81 | GAA (0.34) | RIPK1GAASLC9A1DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |