Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631229 | 0.78 | KMT2A (0.47) | CCR6KMT2ASMN1; SMN2 | |
| SCHEMBL14228794 | 0.78 | KMT2A (0.47) | CCR6KMT2ASMN1; SMN2 | |
| SCHEMBL4631860 | 0.78 | KMT2A (0.47) | CCR6KMT2ASMN1; SMN2 | |
| SCHEMBL24377697 | 0.77 | CA1 (0.36) | KMT2A | |
| SCHEMBL14228751 | 0.77 | CA1 (0.33) | KMT2A | |
| SCHEMBL15286031 | 0.77 | CA1 (0.36) | KMT2A | |
| SCHEMBL13943016 | 0.76 | ADRA2A (0.35) | CCR6 | |
| SCHEMBL6865388 | 0.76 | CA1 (0.45) | CCR6KMT2ASMN1; SMN2 | |
| SCHEMBL3146259 | 0.76 | CA1 (0.45) | CCR6KMT2ASMN1; SMN2 | |
| SCHEMBL12721211 | 0.75 | METAP1 (0.38) | CCR6HSP90AA1MITFMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365096-B2 | Methods for selectively inhibiting Janus tyrosine kinase 3 (Jak3) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-04-29 | — | — | US | disclosed |