Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15286031 | 0.81 | CA1 (0.36) | CA1CA2CA4CA6KMT2A | |
| SCHEMBL24377697 | 0.81 | CA1 (0.36) | CA1CA2CA4CA6KMT2A | |
| SCHEMBL14229576 | 0.77 | CCR6 (0.40) | KMT2A | |
| SCHEMBL12753799 | 0.75 | CA1 (0.47) | CA1CA2CA4CA6KMT2A | |
| SCHEMBL16583761 | 0.74 | CA1 (0.30) | CA1CA2CA4CA6 | |
| SCHEMBL2332955 | 0.73 | — | — | |
| SCHEMBL4636246 | 0.73 | — | — | |
| SCHEMBL16590754 | 0.72 | NLRP3 (0.33) | CA1CA2CA4CA6KMT2A | |
| SCHEMBL16583762 | 0.72 | FBP1 (0.31) | CA1CA2CA4CA6 | |
| SCHEMBL16590753 | 0.69 | KMT2A (0.56) | CA1CA2CA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365096-B2 | Methods for selectively inhibiting Janus tyrosine kinase 3 (Jak3) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-04-29 | — | — | US | disclosed |