Sugi Predict

Sugi Predict / Compounds / SCHEMBL1423027

SCHEMBL1423027

SCHEMBL1423027

CCCCCCCCCCCCc1ccc(Nc2cccc(Nc3ccc(CCCCCCCCCCCC)cc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ UNG P13051 3/20 0.54
▸ ESR1 P03372 2/20 0.50
▸ ADRA2A P08913 2/20 0.50
▸ ADORA3 P0DMS8 2/20 0.50
▸ TACR2 P21452 2/20 0.50
▸ SLC6A2 P23975 2/20 0.50
▸ SLC6A4 P31645 2/20 0.50
▸ SLC6A3 Q01959 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ SHBG P04278 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ HSPD1 P10809 1/20 0.50
▸ ADRB3 P13945 1/20 0.50
▸ HTR2C P28335 1/20 0.50
▸ HSPE1 P61604 1/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ TST Q16762 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9274463 0.93 HPGD (0.50) UNGALDH1A1LMNATP53HSD17B10
SCHEMBL1423225 0.91 UNG (0.57) UNGESR1ADRA2AADORA3TACR2
SCHEMBL7651565 0.91 NPSR1 (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL24570956 0.90 MAPT (0.55) UNGSLC6A2ALDH1A1LMNATP53
SCHEMBL21634393 0.89 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL2493792 0.89 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL449939 0.89 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL11204938 0.89 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL27480376 0.89 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL19986529 0.89 PTGS2 (0.56) UNGESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294257-B1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES CO (US) 2014-01-22 — — EP disclosed
EP-2294257-B1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES CO (US) 2014-01-22 — — EP disclosed
US-8613795-B2 Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-12-24 — — US disclosed
US-20110154987-A1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY 2011-06-30 — — US disclosed
US-20110137082-A1 CHARGE-ENHANCING ADDITIVES FOR ELECTRETS 3M INNOVATIVE PROPERTIES COMPANY 2011-06-09 — — US disclosed
EP-2297086-A2 CHARGE-ENHANCING ADDITIVES FOR ELECTRETS 3M Innovative Properties Company (US) 2011-03-23 — — EP disclosed
WO-2009148744-A2 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-10 — — WO disclosed
WO-2009148747-A2 CHARGE-ENHANCING ADDITIVES FOR ELECTRETS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-10 — — WO disclosed
WO-2009148747-A2 CHARGE-ENHANCING ADDITIVES FOR ELECTRETS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110137082-A1 CHARGE-ENHANCING ADDITIVES FOR ELECTRETS NR4A3, NR4A2, NCOA4 UNG 4622/4885ESR1 76/4885ADRA2A 538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.