SCHEMBL7651565

SCHEMBL7651565

CCCCCCCCCCCCc1ccc(Nc2cccc(C)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.54
UNG P13051 3/20 0.49
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ESR1 P03372 2/20 0.45
ADRA2A P08913 2/20 0.45
ADORA3 P0DMS8 2/20 0.45
TACR2 P21452 2/20 0.45
SLC6A2 P23975 2/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
SHBG P04278 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
HSPD1 P10809 1/20 0.45
ADRB3 P13945 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033939 0.94 NPSR1 (0.58) NPSR1GAAMEN1KMT2AALDH1A1
SCHEMBL1423027 0.91 UNG (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL4547563 0.87 NFKB1 (0.52) NPSR1LMNATP53NPC1POLB
SCHEMBL9274463 0.84 HPGD (0.50) NPSR1UNGGAAMEN1KMT2A
SCHEMBL11204938 0.84 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL2687626 0.84 ESR1 (0.53) UNGGAAMEN1KMT2AESR1
SCHEMBL27480376 0.84 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL449939 0.84 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL21634393 0.84 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2
SCHEMBL2493792 0.84 HTR2A (0.54) UNGESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS CORPORATION 2018-03-22 US disclosed
US-20020076632-A1 High mobility charge transporting molecules for a charge transport layer XEROX CORPORATION 2002-06-20 US disclosed
EP-0027003-B1 A PROCESS FOR PREPARING A DIARYLAMINE XEROX CORPORATION (US) 1983-06-29 EP disclosed
US-4299983-A Chemical process XEROX CORPORATION (US) 1981-11-10 US disclosed
EP-0027003-A1 A process for preparing a diarylamine XEROX CORPORATION (US) 1981-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS GPX4, CAT, SOD1 NPSR1 3040/4885UNG 39/4885GAA 2059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.