Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.77 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.77 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.77 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 4/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | XBP1 | P17861 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147279 | 0.88 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL13770821 | 0.80 | FGFR1 (0.85) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL17969765 | 0.80 | MEN1 (0.79) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL14231954 | 0.79 | FGFR1 (0.57) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL17969757 | 0.78 | MEN1 (0.71) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL116925 | 0.77 | HSP90AA1 (0.86) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL11793576 | 0.75 | FGFR1 (0.69) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL2901813 | 0.74 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL28917824 | 0.74 | MEN1 (0.62) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL9904567 | 0.74 | MAPT (0.78) | FGFR1FGFR2FGFR4FGFR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |