Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.69 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.69 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.69 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | PTPRC | P08575 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | TDP2 | O95551 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30304915 | 0.86 | APAF1 (0.62) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL28758923 | 0.84 | APAF1 (0.60) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL29834814 | 0.84 | APAF1 (0.60) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL229681 | 0.84 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL30179153 | 0.84 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL11058268 | 0.84 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL10560781 | 0.84 | IDO1 (0.60) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL2901813 | 0.84 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL13770821 | 0.83 | FGFR1 (0.85) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL147279 | 0.83 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937795-A | OXIDATION CATALYSTS, CHELATE COMPOUNDS, QUINONES AND HYDROQUINONES, ABSORPTION 3937795 3937795 | NEW WORLD BUSINESS CORPORATION, A CA CORP. | 1976-02-10 | — | — | US | disclosed |