SCHEMBL17969765

SCHEMBL17969765

Cc1ccc(C2=C(C(=O)c3ccccc3)C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.79
KMT2A Q03164 8/20 0.79
LMNA P02545 5/20 0.79
SMN1; SMN2 Q16637 5/20 0.79
NPSR1 Q6W5P4 5/20 0.79
ALDH1A1 P00352 4/20 0.79
HKDC1 Q2TB90 4/20 0.79
L3MBTL1 Q9Y468 4/20 0.79
XBP1 P17861 2/20 0.79
HSP90AA1 P07900 8/20 0.58
HSP90AB1 P08238 5/20 0.58
POLB P06746 2/20 0.53
MAPT P10636 5/20 0.52
KDM4E B2RXH2 4/20 0.52
HTT P42858 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
NPC1 O15118 3/20 0.52
MAPK1 P28482 2/20 0.52
MPI P34949 2/20 0.52
RAB9A P51151 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969757 0.95 MEN1 (0.71) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL28917824 0.89 MEN1 (0.62) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL5390429 0.89 ALDH1A1 (1.00) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL17969759 0.86 MEN1 (0.59) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL7099523 0.85 MEN1 (0.75) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL8029572 0.84 ALDH1A1 (0.57) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL17969764 0.84 LMNA (0.73) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL30885094 0.83 LMNA (0.88) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL8147516 0.82 LMNA (0.75) MEN1KMT2ALMNASMN1; SMN2NPSR1
SCHEMBL14231952 0.80 FGFR1 (0.77) MEN1KMT2ALMNASMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 EP disclosed