Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.85 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.85 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.85 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.85 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.73 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | XBP1 | P17861 | 2/20 | 0.71 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | SRC | P12931 | 5/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147279 | 0.92 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL29273155 | 0.87 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL5958299 | 0.86 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL17969802 | 0.85 | HSP90AA1 (1.00) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL5390429 | 0.83 | ALDH1A1 (1.00) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL8656807 | 0.83 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL11793576 | 0.83 | FGFR1 (0.69) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL17969803 | 0.82 | HSP90AA1 (0.70) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL14231952 | 0.80 | FGFR1 (0.77) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 | |
| SCHEMBL17969780 | 0.80 | FGFR1 (0.88) | FGFR1FGFR2FGFR4FGFR3HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632814-B1 | Inorganic material surface grafted with charge transport moiety | XEROX CORP (US) | 2013-06-26 | — | — | EP | disclosed |
| US-7560161-B2 | Inorganic material surface grafted with charge transport moiety | XEROX CORPORATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-7232633-B2 | Imaging member having inorganic material filler surface grafted with charge transport moiety | XEROX CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |