Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.46 |
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434097 | 0.87 | AR (0.48) | ARPGRMETAP2RORCRORA | |
| SCHEMBL2431707 | 0.85 | AR (0.46) | ARPGRMETAP2RORCRORA | |
| SCHEMBL14232275 | 0.75 | KDM4E (0.40) | ARPGRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14232282 | 0.75 | RORA (0.34) | ARPGRRORCRORARORB | |
| SCHEMBL2434075 | 0.74 | AR (0.46) | ARPGRMETAP2RORCRORA | |
| SCHEMBL2433002 | 0.72 | NTRK1 (0.42) | ARPGR | |
| SCHEMBL2431886 | 0.72 | AR (0.49) | ARPGRRORC | |
| SCHEMBL2438861 | 0.70 | AR (0.61) | ARPGR | |
| SCHEMBL14232285 | 0.70 | CCR2 (0.35) | RORCRORARORB | |
| SCHEMBL12327791 | 0.69 | AR (0.46) | ARPGRMETAP2RORCRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042571-A2 | SUBSTITUTED INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-10 | — | — | WO | disclosed |