Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623245 | 0.81 | KAT2B (0.34) | MCL1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL16750958 | 0.79 | CA1 (0.50) | CYP2C9ALOX15HSD17B10 | |
| SCHEMBL15574020 | 0.75 | GRIN2D (0.34) | MCL1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL29362822 | 0.74 | MCL1 (0.33) | MCL1 | |
| SCHEMBL13855830 | 0.73 | TSHR (0.38) | MCL1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL16750950 | 0.71 | PPARA (0.48) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL13751664 | 0.71 | HDAC8 (0.36) | MCL1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL21527949 | 0.71 | ALDH1A1 (0.32) | MCL1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL13627733 | 0.71 | TRPA1 (0.47) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL15786475 | 0.71 | PGK1 (0.39) | MCL1HDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9623046-B2 | Amphiphilic Janus-dendrimers | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-04-18 | — | — | US | disclosed |