Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818901 | 0.85 | RAB9A (0.44) | PTPN1ALDH1A1MAPTPDE4BSYK | |
| SCHEMBL16518358 | 0.85 | MAPK1 (0.43) | PTPN1ALDH1A1MAPTPDE4BRAB9A | |
| SCHEMBL7772772 | 0.85 | RAB9A (0.44) | PTPN1ALDH1A1MAPTPDE4BSYK | |
| SCHEMBL7242085 | 0.84 | NPC1 (0.46) | PTPN1PDE4BRAB9ANPC1GAA | |
| SCHEMBL22320334 | 0.84 | PDE4B (0.40) | PTPN1ALDH1A1MAPTPDE4BSYK | |
| SCHEMBL12831493 | 0.82 | PTPN1 (0.39) | PTPN1PDE4BRAB9ANPC1L3MBTL1 | |
| SCHEMBL1423902 | 0.82 | NPC1 (0.41) | PTPN1ALDH1A1PDE4BRAB9ANPC1 | |
| SCHEMBL1423603 | 0.82 | L3MBTL1 (0.42) | PTPN1PDE4BRAB9ANPC1L3MBTL1 | |
| SCHEMBL7161254 | 0.82 | PTPN1 (0.41) | PTPN1PDE4BSMN1; SMN2 | |
| SCHEMBL723314 | 0.82 | PDE4B (0.39) | PTPN1ALDH1A1MAPTPDE4BSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019189287-A1 | ALKYNE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-20110224204-A1 | DI-SUBSTITUTED PHENYL COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. | 2011-09-15 | — | — | US | disclosed |
| EP-2297131-A2 | DI-SUBSTITUTED PHENYL COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | Envivo Pharmaceuticals, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009158467-A2 | DI-SUBSTITUTED PHENYL COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224204-A1 | DI-SUBSTITUTED PHENYL COMPOUNDS | PDE10A, PDE1A, PDE12 | PTPN1 919/4885ALDH1A1 1272/4885MAPT 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.