Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772772 | 1.00 | RAB9A (0.44) | RAB9AMAPTLMNAHPGDPDE4B | |
| SCHEMBL16406595 | 0.95 | MAPT (0.48) | RAB9AMAPTLMNAHPGDPDE4B | |
| SCHEMBL22320334 | 0.86 | PDE4B (0.40) | RAB9AMAPTPDE4BSYKALDH1A1 | |
| SCHEMBL18171755 | 0.85 | PDE4B (0.38) | RAB9AMAPTLMNAHPGDPDE4B | |
| SCHEMBL23907105 | 0.85 | PDE4B (0.39) | RAB9AMAPTPDE4BNPC1PTPN1 | |
| SCHEMBL18362187 | 0.85 | ALDH1A1 (0.45) | RAB9AMAPTPDE4BSYKALDH1A1 | |
| SCHEMBL723314 | 0.85 | PDE4B (0.39) | RAB9AMAPTPDE4BSYKALDH1A1 | |
| SCHEMBL7235885 | 0.85 | ACHE (0.49) | RAB9APDE4BSYKALDH1A1KDM4E | |
| SCHEMBL7772633 | 0.85 | ACHE (0.49) | RAB9APDE4BSYKALDH1A1KDM4E | |
| SCHEMBL7228738 | 0.85 | PDE4B (0.39) | RAB9AMAPTPDE4BSYKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191724-A1 | POLYMERIZATION CATALYST HAVING A TETRADENTATE LIGAND | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2021-09-30 | — | — | WO | disclosed |
| EP-3227304-B1 | FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-01-29 | — | — | EP | disclosed |
| US-20180134817-A1 | Catalyst Compositions and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-05-17 | — | — | US | disclosed |
| US-9410016-B2 | Aromatic polyacetals and articles comprising them | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-08-09 | — | — | US | disclosed |
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-20150025278-A1 | AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2015-01-22 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| US-6541490-B1 | Treating ischemia or reoxygenation injury; preparation from a bipyridine, a benzeneboronic acid and a manganese salt | EUKARION, INC. | 2003-04-01 | — | — | US | disclosed |
| EP-1119573-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6177419-B1 | ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS | EUKARION, INC. | 2001-01-23 | — | — | US | disclosed |
| WO-2000009512-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025278-A1 | AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM | AR, PARP1, PARG | RAB9A 2868/4885MAPT 1051/4885LMNA 1440/4885 |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | RAB9A 4755/4885MAPT 1699/4885LMNA 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.