Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237358 | 0.87 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14237490 | 0.85 | GPR119 (0.42) | GPR119 | |
| SCHEMBL1550611 | 0.85 | GPR119 (0.45) | GPR119EPHX2 | |
| SCHEMBL2542644 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL2450343 | 0.79 | GPR119 (0.53) | GPR119 | |
| SCHEMBL2536207 | 0.78 | GPR119 (0.59) | GPR119 | |
| SCHEMBL2540921 | 0.77 | GPR119 (0.43) | GPR119 | |
| SCHEMBL2540165 | 0.77 | GPR119 (0.57) | GPR119 | |
| Hydrochloric Acid SCHEMBL2542617 | 0.77 | GPR119 (0.42) | GPR119 | |
| SCHEMBL2452397 | 0.76 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313395-B1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |