Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 12/20 | 0.34 |
| ▸ | GPR6 | P46095 | 5/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237689 | 0.87 | GPR119 (0.37) | GPR119KDM1ANR3C2 | |
| SCHEMBL14237616 | 0.85 | GPR119 (0.39) | GPR119 | |
| SCHEMBL1550309 | 0.84 | GPR119 (0.43) | GPR119KDM1ANR3C2 | |
| SCHEMBL1550702 | 0.81 | GPR119 (0.58) | GPR119 | |
| SCHEMBL14237635 | 0.79 | NPC1 (0.33) | GPR6 | |
| SCHEMBL2544987 | 0.78 | GPR119 (0.50) | GPR119 | |
| SCHEMBL14237366 | 0.78 | GPR119 (0.36) | GPR119KDM1A | |
| SCHEMBL14237295 | 0.78 | GPR119 (0.38) | GPR119KDM1A | |
| SCHEMBL2538658 | 0.77 | KDM1A (0.41) | KDM1A | |
| Hydrochloric Acid SCHEMBL2546008 | 0.76 | KDM1A (0.41) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313395-B1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |