Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775892 | 0.87 | ACKR3 (0.49) | MAPTL3MBTL1ACRALDH1A1ACKR3 | |
| SCHEMBL2032412 | 0.87 | ACKR3 (0.49) | MAPTL3MBTL1ACRALDH1A1ACKR3 | |
| SCHEMBL29775738 | 0.85 | L3MBTL1 (0.53) | MAPTL3MBTL1ACRALDH1A1TP53 | |
| SCHEMBL16111931 | 0.85 | L3MBTL1 (0.53) | MAPTL3MBTL1ACRALDH1A1TP53 | |
| SCHEMBL21047410 | 0.83 | L3MBTL1 (0.47) | MAPTL3MBTL1ACRLMNACYP1A2 | |
| SCHEMBL21523795 | 0.83 | MAPT (0.51) | MAPTL3MBTL1ACRLMNACYP1A2 | |
| SCHEMBL29775653 | 0.83 | L3MBTL1 (0.47) | MAPTL3MBTL1ACRLMNACYP1A2 | |
| SCHEMBL14167735 | 0.82 | TP53 (0.51) | MAPTL3MBTL1ACRLMNAALDH1A1 | |
| SCHEMBL21523692 | 0.80 | SCD5 (0.48) | MAPTL3MBTL1ACRLMNACYP1A2 | |
| SCHEMBL26923955 | 0.80 | L3MBTL1 (0.47) | MAPTL3MBTL1ACRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168315-A1 | SUBSTITUTED PIPERIDINES AS GPR119 MODULATORS FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-13 | — | — | WO | disclosed |