SCHEMBL26923955

SCHEMBL26923955

CCOC(=O)c1cc(-c2ccc(F)c(O)c2F)on1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 8/20 0.44
ACR P10323 1/20 0.43
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
TP53 P04637 3/20 0.42
ALDH1A1 P00352 4/20 0.42
THRB P10828 1/20 0.41
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
MCL1 Q07820 1/20 0.40
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29775653 0.91 L3MBTL1 (0.47) L3MBTL1MAPTACRHSP90AA1HSP90AB1
SCHEMBL21047410 0.91 L3MBTL1 (0.47) L3MBTL1MAPTACRHSP90AA1HSP90AB1
SCHEMBL26690705 0.86 ALDH1A1 (0.42) L3MBTL1MAPTACRHSP90AA1HSP90AB1
SCHEMBL29775738 0.85 L3MBTL1 (0.53) L3MBTL1MAPTACRTP53ALDH1A1
SCHEMBL16111931 0.85 L3MBTL1 (0.53) L3MBTL1MAPTACRTP53ALDH1A1
SCHEMBL1544635 0.84 L3MBTL1 (0.54) L3MBTL1MAPTACRTP53ALDH1A1
SCHEMBL29775892 0.82 ACKR3 (0.49) L3MBTL1MAPTACRTP53ALDH1A1
SCHEMBL2032412 0.82 ACKR3 (0.49) L3MBTL1MAPTACRTP53ALDH1A1
SCHEMBL21523795 0.81 MAPT (0.51) L3MBTL1MAPTACRTP53ALDH1A1
SCHEMBL14239264 0.80 MAPT (0.43) L3MBTL1MAPTACRHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340546-A1 HSD17B13 INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2025-11-06 US disclosed
CN-119317627-A HSD17B13 inhibitors 勃林格殷格翰国际有限公司 2025-01-14 CN disclosed
WO-2023237504-A1 HSD17B13 INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-12-14 WO disclosed
WO-2023237504-A1 HSD17B13 INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340546-A1 HSD17B13 INHIBITORS HSD17B3, HSD17B13, HSD17B1 L3MBTL1 3702/4885MAPT 4194/4885ACR 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.