Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14239669 | 0.86 | MAPT (0.50) | KDM4EMAPTTHRBGPR119IGF1R | |
| SCHEMBL14240506 | 0.85 | IGF1R (0.49) | KDM4EMAPTTHRBGPR119IGF1R | |
| SCHEMBL6629639 | 0.82 | HTT (0.52) | KDM4EMAPTTHRBGPR119HTT | |
| SCHEMBL25121090 | 0.80 | GPR119 (0.51) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL25719736 | 0.80 | GPR119 (0.51) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL14240497 | 0.80 | KDM4E (0.51) | KDM4EMAPTTHRBGPR119HTT | |
| SCHEMBL27188465 | 0.79 | KDM4E (0.43) | KDM4EMAPTTHRBGPR119 | |
| SCHEMBL22122771 | 0.79 | HPGDS (0.46) | KDM4EMAPTTHRB | |
| SCHEMBL20042188 | 0.78 | MAPT (0.54) | MAPTGPR119 | |
| SCHEMBL20281515 | 0.77 | PDE4B (0.55) | KDM4EMAPTTHRBGPR119IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2719696-A1 | NOVEL KINASE INHIBITORS | Asinex Limited (RU) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012169934-A1 | NOVEL KINASE INHIBITORS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "АСИНЭКС МЕДХИМ" (RU) | 2012-12-13 | — | — | WO | disclosed |