Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.68 |
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14239787 | 0.93 | DNM1 (0.59) | DNM1LPAR1LPAR2ENPP2EPHX2 | |
| SCHEMBL8920345 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL8921826 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL303966 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL8922042 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL8921681 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL20856388 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL8920199 | 0.90 | DGKA (0.67) | DNM1DGKAL3MBTL1FAAHLPAR1 | |
| SCHEMBL17613241 | 0.86 | DNM1 (0.60) | DNM1DGKAL3MBTL1FAAHCASP2 | |
| SCHEMBL21302767 | 0.85 | DGKA (0.59) | DNM1DGKAL3MBTL1FAAHLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170952-A9 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2013-02-21 | — | — | WO | disclosed |
| WO-2012170952-A2 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2012-12-13 | — | — | WO | disclosed |