Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14239783 | 0.93 | DNM1 (0.68) | DNM1LPAR1LPAR2ENPP2EPHX2 | |
| SCHEMBL9860855 | 0.91 | LPAR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL9860844 | 0.91 | LPAR1 (0.67) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL21302818 | 0.88 | CNR1 (0.70) | LPAR1LPAR2ENPP2CNR1ALDH1A1 | |
| SCHEMBL5343029 | 0.86 | EPHX2 (0.58) | DNM1LPAR1LPAR2ENPP2EPHX2 | |
| SCHEMBL5343022 | 0.86 | EPHX2 (0.58) | DNM1LPAR1LPAR2ENPP2EPHX2 | |
| SCHEMBL9472268 | 0.85 | EPHX2 (0.66) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL9472257 | 0.85 | EPHX2 (0.66) | LPAR1LPAR2ENPP2EPHX2CNR1 | |
| SCHEMBL25134837 | 0.85 | DNM1 (0.82) | DNM1LPAR1EPHX2CNR1ALDH1A1 | |
| SCHEMBL22439648 | 0.85 | DNM1 (0.69) | DNM1EPHX2CNR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170952-A9 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2013-02-21 | — | — | WO | disclosed |
| WO-2012170952-A2 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2012-12-13 | — | — | WO | disclosed |