SCHEMBL14239784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17586403	0.97	DNM1 (0.63)	DNM1MGLLEPHX2ALDH1A1MAPT
	SCHEMBL18350944	0.96	DNM1 (0.59)	DNM1MGLLALDH1A1MAPTTHRB
	SCHEMBL21026912	0.94	DNM1 (0.59)	DNM1MGLLEPHX2ALDH1A1MAPT
	SCHEMBL12179617	0.94	DNM1 (0.65)	DNM1MGLLEPHX2ALDH1A1MAPT
	SCHEMBL22269543	0.93	DNM1 (0.55)	DNM1MGLLALDH1A1MAPTTHRB
	SCHEMBL21026929	0.93	DNM1 (0.55)	DNM1MGLLEPHX2ALDH1A1MAPT
	SCHEMBL18350892	0.93	DNM1 (0.58)	DNM1MGLLEPHX2ALDH1A1MAPT
	SCHEMBL17877550	0.93	DNM1 (0.58)	DNM1MGLLALDH1A1MAPTTHRB
	SCHEMBL15027026	0.93	DNM1 (0.57)	DNM1MGLLEPHX2ALDH1A1MAPT
	SCHEMBL17613217	0.92	DNM1 (0.57)	DNM1MGLLEPHX2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.