Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 1.00 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 1.00 |
| ▸ | LDHB | P07195 | 3/20 | 0.43 |
| ▸ | TERF2IP | Q9NYB0 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27013344 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL136097 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL18902502 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL7799155 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL16549195 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL23626629 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL19532503 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL15507051 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| SCHEMBL21991628 | 1.00 | KDM1A (1.00) | KDM1ARCOR1LDHBTERF2IPEGFR | |
| Polymyxin B2 SCHEMBL29514784 | 0.99 | KDM1A (0.98) | KDM1ARCOR1LDHBTERF2IPEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162262-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | Centauri Therapeutics Limited (GB/GB) (GB) | 2022-05-26 | — | — | US | disclosed |
| US-11014966-B2 | Compounds and therapeutics uses thereof | CENTUARI THERAPEUTICS LIMITED (GB) | 2021-05-25 | — | — | US | disclosed |
| EP-3512544-B1 | PEPTIDE COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LTD (GB) | 2020-10-28 | — | — | EP | disclosed |
| WO-2020201743-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2020-10-08 | — | — | WO | disclosed |
| US-20200069767-A1 | NOVEL COMPOUNDS AND THERAPEUTICS USES THEREOF | Centauri Therapeutics Limited (GB/GB) (GB) | 2020-03-05 | — | — | US | disclosed |
| US-20190315806-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CAMS (CN) | 2019-10-17 | — | — | US | disclosed |
| US-20190248838-A1 | NOVEL COMPOUNDS AND THERAPEUTICS USES THEREOF | Centauri Therapeutics Limited (GB/GB) (GB) | 2019-08-15 | — | — | US | disclosed |
| WO-2018051085-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2018-03-22 | — | — | WO | disclosed |
| US-20120316105-A1 | Polymyxin Derivates Useful As Antibacterial Agents | PFIZER INC. | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248838-A1 | NOVEL COMPOUNDS AND THERAPEUTICS USES THEREOF | MAVS, MYD88, CD47 | KDM1A 4216/4885RCOR1 3890/4885LDHB 1565/4885 |
| US-20190315806-A1 | POLYMYXIN DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | NPEPPS, MYD88, MRPL21 | KDM1A 2143/4885RCOR1 1398/4885LDHB 2499/4885 |
| US-11014966-B2 | Compounds and therapeutics uses thereof | MYD88, MAVS, CD47 | KDM1A 4104/4885RCOR1 4159/4885LDHB 1352/4885 |
| US-20200069767-A1 | NOVEL COMPOUNDS AND THERAPEUTICS USES THEREOF | MAVS, MYD88, CD47 | KDM1A 4216/4885RCOR1 3890/4885LDHB 1565/4885 |
| US-20220162262-A1 | NOVEL COMPOUNDS AND THERAPEUTIC USES THEREOF | MAVS, MYD88, CD47 | KDM1A 4412/4885RCOR1 3851/4885LDHB 1356/4885 |
| US-20120316105-A1 | Polymyxin Derivates Useful As Antibacterial Agents | NPEPPS, MDN1, PNKP | KDM1A 3854/4885RCOR1 4836/4885LDHB 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.