SCHEMBL14243152

SCHEMBL14243152

COc1ccc(C(O)(c2ccc(C=O)c(C=O)c2)c2ccc(OC)c(C=O)c2)cc1C=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP19A1 P11511 1/20 0.42
GLO1 Q04760 1/20 0.42
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
ERN1 O75460 7/20 0.41
TUBB1 Q9H4B7 1/20 0.40
TRIM24 O15164 1/20 0.40
TYR P14679 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
TLR2 O60603 1/20 0.40
TLR1 Q15399 1/20 0.40
TLR6 Q9Y2C9 1/20 0.40
AOX1 Q06278 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
PRKDC P78527 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14242951 0.95 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ETDP1CYP19A1
SCHEMBL16233094 0.88 ALDH1A1 (0.53) ALDH1A1TSHRKDM4ETDP1CYP19A1
SCHEMBL14243153 0.84 ALDH1A1 (0.40) ALDH1A1TSHRKDM4ETDP1CYP19A1
SCHEMBL7614307 0.83 ALDH1A1 (0.48) ALDH1A1TSHRKDM4ETDP1LMNA
SCHEMBL4186655 0.80 ALDH1A1 (0.52) ALDH1A1TSHRKDM4ETDP1LMNA
SCHEMBL31738417 0.80 ALDH1A1 (0.52) ALDH1A1TSHRKDM4ETDP1LMNA
SCHEMBL8324591 0.79 ALDH1A1 (0.44) ALDH1A1TSHRKDM4ETDP1LMNA
SCHEMBL7137868 0.79 ALDH1A1 (0.44) ALDH1A1TSHRKDM4ETDP1ERN1
SCHEMBL1186123 0.78 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ETDP1LMNA
SCHEMBL6813982 0.77 ALDH1A1 (0.46) ALDH1A1TSHRKDM4ETDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012167364-A1 PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-12-13 WO disclosed