SCHEMBL14243153

SCHEMBL14243153

COc1ccc(C(O)(c2ccc(OC)c(C=O)c2)c2ccc(C(C)=O)c(C=O)c2)cc1C=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 1/20 0.40
ERN1 O75460 3/20 0.39
TLR2 O60603 1/20 0.39
TLR1 Q15399 1/20 0.39
TLR6 Q9Y2C9 1/20 0.39
LMNA P02545 3/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP19A1 P11511 1/20 0.38
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
HTT P42858 2/20 0.37
HPGD P15428 2/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 1/20 0.37
TUBB1 Q9H4B7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14242951 0.88 ALDH1A1 (0.50) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL14243152 0.84 ALDH1A1 (0.46) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL16233094 0.81 ALDH1A1 (0.53) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL7614307 0.77 ALDH1A1 (0.48) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL7616411 0.77 ALDH1A1 (0.48) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL7583554 0.77 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL4186655 0.74 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL31738417 0.74 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL7137868 0.74 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1TSHRERN1
SCHEMBL8324591 0.74 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1TSHRERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012167364-A1 PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-12-13 WO disclosed