Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GNG2 | P59768 | 2/20 | 0.40 |
| ▸ | GNB1 | P62873 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390992 | 0.81 | TDP1 (0.50) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL3218994 | 0.81 | TDP1 (0.50) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL116082 | 0.81 | TDP1 (0.50) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL1424613 | 0.81 | NQO2 (0.46) | MAPK1ALDH1A1SMN1; SMN2POLBKMT2A | |
| Potassium SCHEMBL30575490 | 0.79 | TDP1 (0.48) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL1404403 | 0.79 | TDP1 (0.48) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL28002634 | 0.79 | TDP1 (0.48) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| Butanedione SCHEMBL7585559 | 0.79 | TDP1 (0.44) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| Dimethylamine SCHEMBL17110604 | 0.79 | TDP1 (0.44) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL2348206 | 0.78 | TDP1 (0.47) | TDP1MAPK1ALDH1A1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608624-B1 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| CN-100519532-C | 6-alkyl-or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-07-29 | — | — | CN | disclosed |
| US-7432227-B2 | 6-alkyl or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-10-07 | — | — | US | disclosed |
| CN-1764646-A | 6-alkyl-or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-04-26 | — | — | CN | disclosed |
| EP-1608624-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004089906-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | AADAC, AASDHPPT, AADAT | TDP1 3420/4885MAPK1 4015/4885ALDH1A1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.