Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227750 | 0.79 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL30945319 | 0.76 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL10688254 | 0.76 | ALDH1A1 (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL5313485 | 0.76 | ALDH1A1 (0.47) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL31536932 | 0.76 | HSD17B10 (0.48) | TSHRLMNAALDH1A1TDP1HSD17B10 | |
| SCHEMBL345760 | 0.76 | HSD17B10 (0.48) | TSHRLMNAALDH1A1TDP1HSD17B10 | |
| SCHEMBL351824 | 0.76 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL12275570 | 0.76 | TSHR (0.45) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL18000477 | 0.76 | TSHR (0.47) | TSHRLMNAALDH1A1TDP1HSD17B10 | |
| SCHEMBL11733678 | 0.74 | HSP90AA1 (0.44) | TSHRLMNAALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000692-A1 | Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors | AURIGENE ONCOLOGY LIMITED (IN) | 2026-01-01 | — | — | US | disclosed |
| US-12319654-B2 | Inert nanocapsules | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2025-06-03 | — | — | US | disclosed |
| CN-119562812-A | Substituted N- (pyridin-2-yl) acetamide derivatives as CDK12/13 inhibitors | 奥里吉恩肿瘤学有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024009232-A1 | SUBSTITUTED N-(PYRIDIN-2-YL)ACETAMIDE DERIVATIVES AS CDK12/13 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2024-01-11 | — | — | WO | disclosed |
| CN-115160220-A | Synthesis process of pyridine-N-oxide | 上海泰坦科技股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20220177431-A1 | INERT NANOCAPSULES | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2022-06-09 | — | — | US | disclosed |
| EP-3318561-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2021-12-22 | — | — | EP | disclosed |
| EP-3823678-A1 | INERT NANOCAPSULES | The University Court Of The University of Edinburgh (GB) | 2021-05-26 | — | — | EP | disclosed |
| US-10562916-B2 | Substituted quinoxalines as PDE-10 inhibitors | SUNOVION PHARMACEUTICALS, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| WO-2020016561-A1 | INERT NANOCAPSULES | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-01-23 | — | — | WO | disclosed |
| US-4738969-A | Substituted aminopyridones and aminoquinolones having histamine H2 -receptor blocking activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-04-19 | — | — | US | disclosed |
| EP-0243450-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1987-11-04 | — | — | EP | disclosed |
| US-4681883-A | Histamine H2 -antagonist oxazole and thiazole derivatives and compositions therefor | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-07-21 | — | — | US | disclosed |
| CN-86107258-A | Pyridyl carbamide compound and on agricultural, using | — | 1987-05-27 | — | — | CN | disclosed |
| WO-1987002665-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC CORPORATION (US) | 1987-05-07 | — | — | WO | disclosed |
| US-4608380-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-08-26 | — | — | US | disclosed |
| CN-85108132-A | Compounds process for production thereof | — | 1986-07-16 | — | — | CN | disclosed |
| EP-0181163-A2 | Heterocyclic phenoxy derivatives having an antihistamine H2 activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-05-14 | — | — | EP | disclosed |
| EP-0143630-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-05 | — | — | EP | disclosed |
| US-4216327-A | 2-(2-Acetylhydrazino)-4-nitropyridine 1-oxide | MORTON-NORWICH PRODUCTS, INC. (US) | 1980-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12319654-B2 | Inert nanocapsules | CHRM2, CHRM5, NCL | TSHR 2935/4885LMNA 690/4885ALDH1A1 4254/4885 |
| US-20260000692-A1 | Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors | CDK1, CDK12, CDK11A | TSHR 1244/4885LMNA 589/4885ALDH1A1 4612/4885 |
| US-20220177431-A1 | INERT NANOCAPSULES | CHRM2, CHRM5, CLN6 | TSHR 2904/4885LMNA 629/4885ALDH1A1 4216/4885 |
| US-10562916-B2 | Substituted quinoxalines as PDE-10 inhibitors | PDE4A, PDE2A, PDE9A | TSHR 2874/4885LMNA 3129/4885ALDH1A1 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.