SCHEMBL351824

SCHEMBL351824

Cc1cc([N+](=O)[O-])cc[n+]1[O-]

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.48
ALDH1A1 P00352 6/20 0.48
TDP1 Q9NUW8 4/20 0.48
ACHE P22303 2/20 0.47
CYP3A4 P08684 2/20 0.46
LMNA P02545 1/20 0.45
HSD17B10 Q99714 2/20 0.43
MAPT P10636 3/20 0.41
MITF O75030 1/20 0.38
PTPRC P08575 2/20 0.38
S100A4 P26447 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945319 1.00 TSHR (0.48) TSHRALDH1A1TDP1ACHECYP3A4
SCHEMBL10353692 0.90 TSHR (0.43) TSHRALDH1A1TDP1ACHECYP3A4
SCHEMBL15354544 0.80 TSHR (0.48) TSHRALDH1A1TDP1ACHECYP3A4
SCHEMBL3087524 0.79 TSHR (0.41) TSHRALDH1A1TDP1ACHECYP3A4
SCHEMBL2227750 0.79 TSHR (0.48) TSHRALDH1A1TDP1ACHECYP3A4
SCHEMBL18000477 0.76 TSHR (0.47) TSHRALDH1A1TDP1LMNAHSD17B10
SCHEMBL12275570 0.76 TSHR (0.45) TSHRALDH1A1TDP1ACHECYP3A4
SCHEMBL31536932 0.76 HSD17B10 (0.48) TSHRALDH1A1TDP1ACHELMNA
SCHEMBL345760 0.76 HSD17B10 (0.48) TSHRALDH1A1TDP1ACHELMNA
SCHEMBL1424323 0.76 TSHR (0.45) TSHRALDH1A1TDP1ACHECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326709-A1 THE MICROWAVE-ASSISTED CATALYTIC AMIDATION OF ORGANIC AMINES WITH CARBOXYLIC ACIDS PURDUE RESEARCH FOUNDATION (US) 2025-10-23 US claimed
WO-2025059054-A1 PROCESS FOR PREPARING (2S,4S,4'S,6S)-2-METHYL-6-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-2',-(TRIELUOROMETHYL)-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO [2,3-C] PYRAN] -4'-OL VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-03-20 WO claimed
CN-115197046-B Halogenation method of unsaturated hydrocarbon 华南理工大学 2023-12-15 CN claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
US-20080051519-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2008-02-28 US claimed
EP-0397474-B1 Photosensitive composition TOSHIBA KK (JP) 1997-12-10 EP claimed
US-5100768-A Photoresists for integrated circuits, polyvinyl phenol and nitrogen containing heterocycle KABUSHIKI KAISHA TOSHIBA (JP) 1992-03-31 US claimed
EP-0397474-A2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 1990-11-14 EP claimed
CN-122059908-A Method for preparing propylene oxide by catalyzing propylene air epoxidation through double metal-free catalysts 浙江工业大学 2026-05-19 CN disclosed
US-20250326709-A1 THE MICROWAVE-ASSISTED CATALYTIC AMIDATION OF ORGANIC AMINES WITH CARBOXYLIC ACIDS PURDUE RESEARCH FOUNDATION (US) 2025-10-23 US disclosed
EP-4619048-A1 CYCLEN BASED COMPOUNDS AND THEIR GD(III) COMPLEXES FOR USE AS MULTIMODAL PET/MRI CONTRAST AGENTS Ustav Organicke Chemie a Biochemie AV CR v.v.i. (CZ) 2025-09-24 EP disclosed
WO-2025059054-A1 PROCESS FOR PREPARING (2S,4S,4'S,6S)-2-METHYL-6-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-2',-(TRIELUOROMETHYL)-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO [2,3-C] PYRAN] -4'-OL VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-03-20 WO disclosed
WO-2024120557-A1 CYCLEN BASED COMPOUNDS AND THEIR GD(III) COMPLEXES FOR USE AS MULTIMODAL PET/MRI CONTRAST AGENTS Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) 2024-06-13 WO disclosed
EP-0175464-A1 Benzimidazole derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1986-03-26 EP disclosed
EP-0138983-A4 N-PHENYL-N'-(PYRIDINYL-N-OXIDE)UREA PLANT REGULATORS. FMC CORP (US) 1985-07-30 EP disclosed
EP-0144230-A2 Growth promotants for animals Pfizer Limited (GB) 1985-06-12 EP disclosed
EP-0138983-A1 N-PHENYL-N'-(PYRIDINYL-N-OXIDE)UREA PLANT REGULATORS. FMC CORP (US) 1985-05-02 EP disclosed
WO-1984003884-A1 N-PHENYL-N'-(PYRIDINYL-N-OXIDE)UREA PLANT REGULATORS FMC CORP (US) 1984-10-11 WO disclosed
US-3966741-A Process for the preparation of substituted or unsubstituted 4-pyridylthioacetic acid OCE-ANDENO B.V. (NL) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326709-A1 THE MICROWAVE-ASSISTED CATALYTIC AMIDATION OF ORGANIC AMINES WITH CARBOXYLIC ACIDS NAAA, OAT, PAM TSHR 2874/4885ALDH1A1 1504/4885TDP1 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.