Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227750 | 0.79 | TSHR (0.48) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL18000477 | 0.76 | TSHR (0.47) | ALDH1A1TDP1TSHRLMNAGAA | |
| SCHEMBL10688254 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL351824 | 0.76 | TSHR (0.48) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL31536932 | 0.76 | HSD17B10 (0.48) | ALDH1A1TDP1TSHRLMNAALOX15 | |
| SCHEMBL12275570 | 0.76 | TSHR (0.45) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL30945319 | 0.76 | TSHR (0.48) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL1424323 | 0.76 | TSHR (0.45) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL345760 | 0.76 | HSD17B10 (0.48) | ALDH1A1TDP1TSHRLMNAALOX15 | |
| SCHEMBL5821067 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |