Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.71 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426058 | 1.00 | HSD17B3 (0.71) | HSD17B3SLC6A19HDAC2HDAC3HDAC1 | |
| SCHEMBL31482396 | 0.89 | HSD17B3 (0.71) | HSD17B3SLC6A19HDAC2HDAC3HDAC1 | |
| SCHEMBL31528763 | 0.88 | MAOB (0.68) | HSD17B3SLC6A19HDAC2HDAC3HDAC1 | |
| SCHEMBL16589017 | 0.84 | BACE1 (0.82) | HSD17B3SLC6A19MAOBMAOABACE1 | |
| SCHEMBL9781847 | 0.83 | SLC6A19 (0.67) | HSD17B3SLC6A19MAOBMAOABACE1 | |
| SCHEMBL9781858 | 0.83 | SLC6A19 (0.67) | HSD17B3SLC6A19MAOBMAOABACE1 | |
| SCHEMBL9781852 | 0.83 | SLC6A19 (0.67) | HSD17B3SLC6A19MAOBMAOABACE1 | |
| SCHEMBL1035543 | 0.83 | HSD17B3 (0.79) | HSD17B3SLC6A19MAOBMAOABACE1 | |
| SCHEMBL1035544 | 0.83 | HSD17B3 (0.79) | HSD17B3SLC6A19MAOBMAOABACE1 | |
| Cinromide SCHEMBL35055 | 0.82 | SLC6A19 (1.00) | HSD17B3SLC6A19MAOBMAOABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260382-B2 | Methods of reducing virulence in bacteria | UWM RESEARCH FOUNDATION (US) | 2016-02-16 | — | — | US | disclosed |
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| US-20120322769-A1 | METHODS OF REDUCING VIRULENCE IN BACTERIA | DUKE UNIVERSITY (US) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322769-A1 | METHODS OF REDUCING VIRULENCE IN BACTERIA | PGLS, RRS1, MRPL21 | HSD17B3 4054/4885SLC6A19 4279/4885HDAC2 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.