SCHEMBL14246769

SCHEMBL14246769

CCCCC(O)C(=O)OC(=O)CCCCC(=O)OC(=O)C(O)CCCC

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.51
TSHR P16473 1/20 0.51
ATM Q13315 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MAPT P10636 2/20 0.49
DGKA P23743 1/20 0.47
LMNA P02545 4/20 0.46
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.43
PAM P19021 2/20 0.43
GPR84 Q9NQS5 3/20 0.42
NAAA Q02083 1/20 0.42
FFAR1 O14842 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527155 0.96 MAPT (0.54) CYP3A4TSHRATMTDP1MAPT
SCHEMBL9722921 0.93 MAPT (0.54) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL665783 0.93 MAPT (0.54) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL9219407 0.93 MAPT (0.54) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL19695188 0.93 MAPT (0.54) MAPTDGKALMNAKDM4EDUSP3
Alcohol SCHEMBL6359960 0.90 LMNA (0.53) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL30439420 0.89 MAPT (0.54) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL31065847 0.87 LMNA (0.50) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL9722954 0.85 GPR84 (0.53) MAPTDGKALMNAKDM4EDUSP3
SCHEMBL2066617 0.84 MAPT (0.50) MAPTDGKALMNAKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2718340-B1 ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS INVISTA TECHNOLOGIES SARL (CH) 2017-08-09 EP disclosed
US-20150274922-A1 MATERIALS COMPRISING NVR POLYOLS INVISTA NORTH AMERICA S.A.R.L. (US) 2015-10-01 US disclosed
US-9056940-B2 Aliphatic polyester polyols from cyclohexane oxidation byproduct streams as precursors for polyurethane and polyisocyanurate polymers INVISTA NORTH AMERICA S.A R. L. (US) 2015-06-16 US disclosed
EP-2718340-A1 ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS Invista Technologies S.à.r.l. (CH) 2014-04-16 EP disclosed
WO-2014047043-A1 MATERIALS COMPRISING NVR POLYOLS INVISTA NORTH AMERICA S.A R.L. (US) 2014-03-27 WO disclosed
US-20130042659-A1 ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS INVISTA NORTH AMERICA S.A R.L (US) 2013-02-21 US disclosed
WO-2012173938-A1 ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS INVISTA TECHNOLOGIES S.A.R.L. (CH) 2012-12-20 WO disclosed