Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219407 | 0.97 | MAPT (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL665783 | 0.97 | MAPT (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL19695188 | 0.97 | MAPT (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9722921 | 0.97 | MAPT (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL11527155 | 0.93 | MAPT (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9722954 | 0.90 | GPR84 (0.53) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL30439420 | 0.90 | MAPT (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL14246769 | 0.90 | CYP3A4 (0.51) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Alcohol SCHEMBL2347057 | 0.88 | LMNA (0.58) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL8609358 | 0.88 | DGKA (0.58) | LMNADUSP3MAPTDGKAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079972-A1 | ELEMENT FOR APPLYING FIBRES TO HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| US-20050172421-A1 | Keratin fibre makeup composition combining high solids content with specific rheological profile | L'OREAL (FR) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050172421-A1 | Keratin fibre makeup composition combining high solids content with specific rheological profile | KRT18, YWHAZ, PRKCZ | LMNA 1188/4885KDM4E 585/4885DUSP3 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.