Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617141 | 1.00 | GPR84 (0.55) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL8764754 | 1.00 | GPR84 (0.55) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL20704565 | 1.00 | GPR84 (0.55) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL4543277 | 0.93 | GPR84 (0.48) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL9722912 | 0.91 | KDM4E (0.48) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL19668390 | 0.91 | GPR84 (0.73) | GPR84FFAR1FFAR4ALDH1A1FNTA | |
| SCHEMBL9722925 | 0.89 | DGKA (0.57) | KDM4ESMN1; SMN2ALDH1A1DGKAMAPT | |
| SCHEMBL29124940 | 0.89 | DGKA (0.57) | KDM4ESMN1; SMN2ALDH1A1DGKAMAPT | |
| SCHEMBL28649860 | 0.89 | GPR84 (0.62) | GPR84FFAR1FFAR4ALDH1A1FNTA | |
| SCHEMBL665784 | 0.89 | DGKA (0.57) | KDM4ESMN1; SMN2ALDH1A1DGKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718340-B1 | ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS | INVISTA TECHNOLOGIES SARL (CH) | 2017-08-09 | — | — | EP | disclosed |
| US-20150274922-A1 | MATERIALS COMPRISING NVR POLYOLS | INVISTA NORTH AMERICA S.A.R.L. (US) | 2015-10-01 | — | — | US | disclosed |
| US-9056940-B2 | Aliphatic polyester polyols from cyclohexane oxidation byproduct streams as precursors for polyurethane and polyisocyanurate polymers | INVISTA NORTH AMERICA S.A R. L. (US) | 2015-06-16 | — | — | US | disclosed |
| EP-2718340-A1 | ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS | Invista Technologies S.à.r.l. (CH) | 2014-04-16 | — | — | EP | disclosed |
| WO-2014047043-A1 | MATERIALS COMPRISING NVR POLYOLS | INVISTA NORTH AMERICA S.A R.L. (US) | 2014-03-27 | — | — | WO | disclosed |
| US-20130042659-A1 | ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS | INVISTA NORTH AMERICA S.A R.L (US) | 2013-02-21 | — | — | US | disclosed |
| WO-2012173938-A1 | ALIPHATIC POLYESTER POLYOLS FROM CYCLOHEXANE OXIDATION BYPRODUCT STREAMS AS PRECURSORS FOR POLYURETHANE AND POLYISOCYANURATE POLYMERS | INVISTA TECHNOLOGIES S.A.R.L. (CH) | 2012-12-20 | — | — | WO | disclosed |