Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617141 | 1.00 | GPR84 (0.55) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL14246770 | 1.00 | GPR84 (0.55) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL20704565 | 1.00 | GPR84 (0.55) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL4543277 | 0.93 | GPR84 (0.48) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL9722912 | 0.91 | KDM4E (0.48) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL19668390 | 0.91 | GPR84 (0.73) | GPR84FFAR1FFAR4ALDH1A1FNTA | |
| SCHEMBL9722925 | 0.89 | DGKA (0.57) | KDM4ESMN1; SMN2ALDH1A1DGKAMAPT | |
| SCHEMBL29124940 | 0.89 | DGKA (0.57) | KDM4ESMN1; SMN2ALDH1A1DGKAMAPT | |
| SCHEMBL28649860 | 0.89 | GPR84 (0.62) | GPR84FFAR1FFAR4ALDH1A1FNTA | |
| SCHEMBL665784 | 0.89 | DGKA (0.57) | KDM4ESMN1; SMN2ALDH1A1DGKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0646572-B1 | Process for the preparation of ceramides | QUEST INT (NL) | 1997-07-23 | — | — | EP | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5525709-A | Process for the preparation of ceramides | UNILEVER PATENT HOLDINGS B.V. (NL) | 1996-06-11 | — | — | US | disclosed |
| EP-0646572-A1 | Process for the preparation of ceramides | QUEST INTERNATIONAL B.V. (NL) | 1995-04-05 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |