Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250560 | 0.92 | HTR2A (0.37) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| SCHEMBL1525666 | 0.92 | HTR2A (0.37) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| SCHEMBL251633 | 0.92 | HTR2A (0.37) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| SCHEMBL3262720 | 0.92 | HTR2A (0.37) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| SCHEMBL7934677 | 0.92 | HTR2A (0.37) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| Phosphoric Acid SCHEMBL7706766 | 0.90 | LTB4R (0.38) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| Acetic Acid SCHEMBL4544163 | 0.90 | LTB4R (0.42) | LTB4RLTB4R2TSHRPPARABID | |
| Sulfuric Acid SCHEMBL6576616 | 0.89 | LTB4R (0.34) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| Acetic Acid SCHEMBL4551109 | 0.88 | LTB4R (0.39) | LTB4RLTB4R2TSHRMEN1KMT2A | |
| Acrylic Acid SCHEMBL1261322 | 0.86 | THRB (0.43) | LTB4RLTB4R2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190039090-A1 | BRILLIANT PIGMENT-CONTAINING AQUEOUS BASE COAT COATING MATERIAL, AND METHOD FOR FORMING MULTILAYER FILM USING SAME | KANSAI PAINT CO., LTD. (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-1380283-B1 | Cosmetic composition | AJINOMOTO KK (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20040052755-A1 | Cosmetic composition | AJINOMOTO CO., INC (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1380283-A1 | Cosmetic composition | Ajinomoto Co., Inc. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-5969037-A | MULTISTAGE EMULSION POLYMERIZATION OF MONOMERS TO FORM PARTICLES WITH A CORE CONTAINING SILYL VINYL MONOMERS WITH VINYL MONOMERS AND A SHELL AND CURING FOR STORAGE STABILITY, WATERPROOFING, DURABILITY AND WHITE GLOSS | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0842961-A1 | COLD CURABLE COMPOSITION | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0621325-B1 | Room temperature curing composition | KANEGAFUCHI CHEMICAL IND (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5668194-A | SHELL-CORE POLYMER FROM UNSATURATED SILICON MONOMER | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0621325-A1 | Room temperature curing composition | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1994-10-26 | — | — | EP | disclosed |