Demannose

Demannose

SCHEMBL14248786

CCOC(C)=O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OCC(O)CO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 1/20 0.42
PDE4A P27815 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
KDM4E B2RXH2 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL5541835 0.95 LMNA (0.47) LMNAALDH1A1HSD17B10PDE4AL3MBTL1
Demannose SCHEMBL11509807 0.95 LMNA (0.47) LMNAALDH1A1HSD17B10PDE4AL3MBTL1
Demannose SCHEMBL14248791 0.85 PDE4A (0.42) LMNAALDH1A1PDE4AL3MBTL1TDP1
Demannose SCHEMBL2587512 0.85 PDE4A (0.45) LMNAALDH1A1PDE4AL3MBTL1TDP1
Xylitol SCHEMBL5836242 0.85 LMNA (0.54) LMNAALDH1A1HSD17B10PDE4AL3MBTL1
Demannose SCHEMBL5394727 0.84 LMNA (0.38) LMNAALDH1A1PDE4AL3MBTL1TDP1
Demannose SCHEMBL16540384 0.84 PDE4A (0.41) LMNAALDH1A1PDE4AL3MBTL1TDP1
Demannose SCHEMBL16879734 0.84 LMNA (0.44) LMNAALDH1A1PDE4AL3MBTL1TDP1
Galactose SCHEMBL8954978 0.84 LMNA (0.44) LMNAALDH1A1PDE4AL3MBTL1TDP1
Galactose SCHEMBL8955405 0.84 LMNA (0.44) LMNAALDH1A1PDE4AL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2721166-A1 IN SITU EXPRESSION OF LIPASE FOR ENZYMATIC PRODUCTION OF ALCOHOL ESTERS DURING FERMENTATION Butamax(tm) Advanced Biofuels LLC (US) 2014-04-23 EP disclosed
WO-2012173658-A1 IN SITU EXPRESSION OF LIPASE FOR ENZYMATIC PRODUCTION OF ALCOHOL ESTERS DURING FERMENTATION BUTAMAX (TM) ADVANCED BIOFUELS LLC (US) 2012-12-20 WO disclosed