Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL11509807 | 1.00 | LMNA (0.47) | LMNAALDH1A1HSD17B10L3MBTL1PDE4A | |
| Demannose SCHEMBL14248786 | 0.95 | LMNA (0.42) | LMNAALDH1A1HSD17B10L3MBTL1PDE4A | |
| Mannitol SCHEMBL27819402 | 0.88 | ALDH1A1 (0.61) | LMNAALDH1A1HSD17B10L3MBTL1PDE4A | |
| Demannose SCHEMBL15066411 | 0.87 | GLO1 (0.40) | LMNAALDH1A1HSD17B10L3MBTL1PDE4A | |
| Demannose SCHEMBL3935915 | 0.85 | LMNA (0.35) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Demannose SCHEMBL20701787 | 0.85 | ALOX15 (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Demannose SCHEMBL20701790 | 0.85 | ALOX15 (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Demannose SCHEMBL8020533 | 0.84 | THRB (0.39) | LMNAALDH1A1L3MBTL1PDE4ATDP1 | |
| Demannose SCHEMBL21274470 | 0.84 | THRB (0.39) | LMNAALDH1A1L3MBTL1PDE4ATDP1 | |
| Demannose SCHEMBL14157347 | 0.84 | THRB (0.39) | LMNAALDH1A1L3MBTL1PDE4ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438580-A4 | COMPOSITIONS AND METHODS FOR MODELING SACCHAROMYCES CEREVISIAE METABOLISM | UNIV CALIFORNIA (US) | 2007-11-14 | — | — | EP | disclosed |
| EP-1438580-A1 | COMPOSITIONS AND METHODS FOR MODELING SACCHAROMYCES CEREVISIAE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003036296-A9 | COMPOSITIONS AND METHODS FOR MODELING SACCHAROMYCES CEREVISIAE METABOLISM | UNIV CALIFORNIA (US) | 2004-05-13 | — | — | WO | disclosed |
| WO-2003036296-A1 | COMPOSITIONS AND METHODS FOR MODELING SACCHAROMYCES CEREVISIAE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-05-01 | — | — | WO | disclosed |