Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.51 |
| ▸ | HNF4A | P41235 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | BAD | Q92934 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363677 | 0.87 | DCLRE1B (0.60) | DCLRE1BESR2DHODHACMSDHNF4A | |
| SCHEMBL2160051 | 0.87 | DCLRE1B (0.60) | DCLRE1BESR2DHODHACMSDHNF4A | |
| SCHEMBL1099041 | 0.86 | ACMSD (0.66) | DCLRE1BACMSDHNF4AMCL1DHFR | |
| SCHEMBL30605782 | 0.86 | ACMSD (0.66) | DCLRE1BACMSDHNF4AMCL1DHFR | |
| SCHEMBL29395437 | 0.86 | ACMSD (0.66) | DCLRE1BACMSDHNF4AMCL1DHFR | |
| SCHEMBL8999909 | 0.86 | ACMSD (0.66) | DCLRE1BACMSDHNF4AMCL1DHFR | |
| SCHEMBL27630318 | 0.86 | ACMSD (0.71) | DCLRE1BESR2DHODHACMSDHNF4A | |
| SCHEMBL3685447 | 0.86 | ACMSD (0.72) | DCLRE1BESR2ACMSDHNF4AMCL1 | |
| SCHEMBL10024256 | 0.84 | DCLRE1B (0.57) | DCLRE1BESR2DHODHACMSDHNF4A | |
| SCHEMBL14089870 | 0.84 | DCLRE1B (0.61) | DCLRE1BESR2DHODHACMSDHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339071-B2 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |