Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.70 |
| ▸ | SERPINC1 | P01008 | 3/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.43 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | CCL2 | P13500 | 1/20 | 0.43 |
| ▸ | CCL5 | P13501 | 1/20 | 0.43 |
| ▸ | BDNF | P23560 | 3/20 | 0.42 |
| ▸ | PTN | P21246 | 2/20 | 0.42 |
| ▸ | MDK | P21741 | 2/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.39 |
| ▸ | FGF1 | P05230 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | BMP2 | P12643 | 1/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | SHH | Q15465 | 1/20 | 0.38 |
| ▸ | FGF2 | P09038 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14706300 | 1.00 | F10 (0.70) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL16502382 | 0.95 | F10 (0.76) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL23337007 | 0.93 | F10 (0.64) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL15199336 | 0.92 | F10 (0.81) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL14665995 | 0.92 | F10 (0.81) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL18883211 | 0.92 | F10 (0.81) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL10157440 | 0.92 | F10 (0.81) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL14960713 | 0.92 | F10 (0.81) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL13130300 | 0.90 | F10 (0.84) | F10SERPINC1CXCL12CXCL10CXCL8 | |
| SCHEMBL16509456 | 0.87 | F10 (0.77) | F10SERPINC1CXCL12CXCL10CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080063627-A1 | Tissue graft materials containing biocompatible agent and methods of making and using same | SURMODICS, INC. | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080063627-A1 | Tissue graft materials containing biocompatible agent and methods of making and using same | COL1A1, COL14A1, PDGFA | F10 211/4885SERPINC1 400/4885CXCL12 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.