SCHEMBL14960713

SCHEMBL14960713

COC1OC(COS(=O)(=O)O)C(OC2OC(C(=O)O)C(OC)C(O)C2OS(=O)(=O)O)C(O)C1NS(=O)(=O)O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.81
SERPINC1 P01008 4/20 0.56
BDNF P23560 3/20 0.44
PTN P21246 2/20 0.44
MDK P21741 2/20 0.44
CXCL12 P48061 3/20 0.44
CCL2 P13500 2/20 0.44
CXCL10 P02778 1/20 0.44
CXCL8 P10145 1/20 0.44
CCL5 P13501 1/20 0.44
F2 P00734 2/20 0.43
FGF1 P05230 3/20 0.42
HPSE Q9Y251 1/20 0.41
FGF2 P09038 1/20 0.40
BMP2 P12643 2/20 0.39
VEGFA P15692 2/20 0.39
SHH Q15465 2/20 0.39
IFNG P01579 1/20 0.39
PF4 P02776 1/20 0.39
SELP P16109 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10157440 1.00 F10 (0.81) F10SERPINC1BDNFPTNMDK
SCHEMBL18883211 1.00 F10 (0.81) F10SERPINC1BDNFPTNMDK
SCHEMBL14665995 1.00 F10 (0.81) F10SERPINC1BDNFPTNMDK
SCHEMBL15199336 1.00 F10 (0.81) F10SERPINC1BDNFPTNMDK
SCHEMBL13130300 0.98 F10 (0.84) F10SERPINC1BDNFPTNMDK
SCHEMBL29308178 0.94 F10 (0.79) F10SERPINC1BDNFPTNMDK
SCHEMBL24064572 0.93 F10 (0.74) F10SERPINC1BDNFPTNMDK
SCHEMBL14252707 0.92 F10 (0.70) F10SERPINC1BDNFPTNMDK
SCHEMBL14706300 0.92 F10 (0.70) F10SERPINC1BDNFPTNMDK
SCHEMBL14666015 0.90 F10 (0.68) F10SERPINC1BDNFPTNMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036234-B2 Heparin conjugated to collagen-binding peptides for targeting to biological and synthetic tissues NORTHWESTERN UNIVERSITY (US) 2024-07-16 US disclosed
US-11795320-B2 Grafted polymer and use thereof BAUSCH + LOMB IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11325987-B2 Solid state nanopores aided by machine learning for identification and quantification of heparins and glycosaminoglycans ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2022-05-10 US disclosed
US-20210369665-A1 METHODS OF TREATING VIRAL INFECTION USING PROTEASE INHIBITORS LOWELL THERAPEUTICS INC (US) 2021-12-02 US disclosed
US-20210299158-A1 Heparin Conjugated to Collagen-Binding Peptides for Targeting to Biological and Synthetic Tissues NORTHWESTERN UNIVERSITY (US) 2021-09-30 US disclosed
US-20190256616-A1 SOLID STATE NANOPORES AIDED BY MACHINE LEARNING FOR IDENTIFICATION AND QUANTIFICATION OF HEPARINS AND GLYCOSAMINOGLYCANS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-08-22 US disclosed
CN-106032527-B It is a kind of tolerance low-density without feeder layer human pluripotent stem cells culture medium 广州市搏克肿瘤研究所 2019-08-13 CN disclosed
WO-2019075213-A1 HEPARIN CONJUGATED TO COLLAGEN-BINDING PEPTIDES FOR TARGETING TO BIOLOGICAL AND SYNTHETIC TISSUES NORTHWESTERN UNIVERSITY (US) 2019-04-18 WO disclosed
CN-106032527-A Low-density-tolerant feeder-layer-free human pluripotency stem cell culture medium 广州市搏克肿瘤研究所 2016-10-19 CN disclosed
US-20130129632-A1 Quantum dot materials, methods for making them, and uses thereof DUKE UNIVERSITY 2013-05-23 US disclosed
US-20130129632-A1 Quantum dot materials, methods for making them, and uses thereof DUKE UNIVERSITY 2013-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369665-A1 METHODS OF TREATING VIRAL INFECTION USING PROTEASE INHIBITORS SERPINB1, TMPRSS15, PRSS1 F10 730/4885SERPINC1 22/4885BDNF 4738/4885
US-20210299158-A1 Heparin Conjugated to Collagen-Binding Peptides for Targeting to Biological and Synthetic Tissues COL14A1, MATR3, COL2A1 F10 209/4885SERPINC1 5/4885BDNF 1273/4885
US-20130129632-A1 Quantum dot materials, methods for making them, and uses thereof CLN6, SOD3, SOD1 F10 4821/4885SERPINC1 4191/4885BDNF 3216/4885
US-12036234-B2 Heparin conjugated to collagen-binding peptides for targeting to biological and synthetic tissues COL14A1, MATR3, COL2A1 F10 209/4885SERPINC1 5/4885BDNF 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.