Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 9/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479594 | 0.79 | F12 (0.37) | F12F2 | |
| SCHEMBL14256177 | 0.76 | F12 (0.37) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| SCHEMBL19656756 | 0.72 | HTR2C (0.46) | HTR2AHTR2CF12F2 | |
| SCHEMBL31552722 | 0.72 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| SCHEMBL11263563 | 0.71 | HTR2C (0.39) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11402316 | 0.71 | HTR2C (0.36) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11267162 | 0.70 | HTR2C (0.38) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| SCHEMBL22492624 | 0.70 | F12 (0.47) | F12F2 | |
| SCHEMBL5477500 | 0.70 | HTR1A (0.33) | SLC6A2SLC6A4SLC6A3HTR1AF12 | |
| SCHEMBL16359911 | 0.69 | F12 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |