Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 6/20 | 0.72 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.69 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.69 |
| ▸ | APP | P05067 | 6/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256778 | 0.90 | MERTK (0.65) | MERTKEHMT2DNMT3AAPPSLC2A1 | |
| SCHEMBL14256774 | 0.90 | APP (0.60) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL14266672 | 0.88 | MERTK (0.57) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL14256541 | 0.88 | MERTK (0.63) | MERTKEHMT2DNMT3AAPPSLC2A1 | |
| SCHEMBL14266664 | 0.87 | APP (0.62) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL24649781 | 0.86 | CXCR4 (0.63) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL30896224 | 0.86 | CXCR4 (0.63) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL14256527 | 0.86 | APP (0.64) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL14256532 | 0.86 | EHMT2 (0.66) | MERTKEHMT2DNMT3AAPPBCHE | |
| SCHEMBL14256525 | 0.86 | CXCR4 (0.56) | MERTKEHMT2DNMT3AAPPBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | HGF, MET, HDGF | MERTK 58/4885EHMT2 1177/4885DNMT3A 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.