Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 7/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.52 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | ACP1 | P24666 | 2/20 | 0.51 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256556 | 0.84 | MERTK (0.81) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL14256561 | 0.83 | MERTK (0.67) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL14256632 | 0.81 | MERTK (0.70) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL14266691 | 0.79 | MERTK (0.50) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL14256538 | 0.79 | MERTK (0.50) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL27224044 | 0.78 | MERTK (0.81) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL24649614 | 0.77 | NPY5R (0.79) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL14256774 | 0.77 | APP (0.60) | MERTKNPY5RPDE5AACP1OGG1 | |
| SCHEMBL14256549 | 0.77 | MERTK (0.58) | MERTKNPY5RTLR7PDE5AACP1 | |
| SCHEMBL14256531 | 0.76 | MERTK (0.65) | MERTKNPY5RACP1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | HGF, MET, HDGF | MERTK 58/4885NPY5R 3095/4885TLR7 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.