Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 10/20 | 0.46 |
| ▸ | CTSL | P07711 | 9/20 | 0.46 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146358 | 0.86 | SYK (0.53) | SYKCTRB1CTSSCTSLCTSB | |
| SCHEMBL5196294 | 0.86 | SYK (0.53) | SYKCTRB1CTSSCTSLCTSB | |
| SCHEMBL143122 | 0.86 | SYK (0.53) | SYKCTRB1CTSSCTSLCTSB | |
| SCHEMBL143177 | 0.83 | SYK (0.50) | SYKCTRB1CTSSCTSLCTSB | |
| SCHEMBL16336595 | 0.82 | SYK (0.59) | SYKCTRB1CTSSCTSLCTSB | |
| SCHEMBL2776839 | 0.81 | CTSK (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL42878 | 0.81 | CTSK (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL27857330 | 0.81 | CTSK (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL142588 | 0.78 | SYK (0.55) | SYKCTRB1CTSSCTSLCTSB | |
| SCHEMBL116476 | 0.78 | CTRB1 (0.51) | SYKCTRB1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | SYK 4291/4885CTRB1 163/4885CTSS 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.