Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10579646 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL29076620 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3358951 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9145494 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL121569 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL23415 | 0.86 | — | — | |
| Bicarbonate SCHEMBL618448 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL20604683 | 0.86 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21951326 | 0.86 | — | — | |
| Bicarbonate SCHEMBL1270395 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122037931-A | Gallium aluminate near-infrared luminescent material, preparation method thereof and near-infrared LED luminescent device | 重庆邮电大学 | 2026-05-15 | — | — | CN | claimed |
| US-12529154-B2 | Electrode for electrolysis | LG CHEM, LTD. (KR) | 2026-01-20 | — | — | US | claimed |
| CN-119976931-A | Synthesis method of high-purity anhydrous rare earth fluoride | 中国科学院上海有机化学研究所 | 2025-05-13 | — | — | CN | claimed |
| CN-119570482-A | Bi3+、Yb3+Co-doped Cs2ZrCl6Double perovskite microcrystal and preparation method of light conversion film thereof | 北京工业大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119462111-A | Multi-element rare earth silicate/silicon oxygen carbon nano multiphase ceramic and preparation method thereof | 中南大学 | 2025-02-18 | — | — | CN | claimed |
| CN-117070221-B | Yb (Yb)3+Holmium-based chloride-doped double perovskite material, and preparation method and application thereof | 武汉理工大学 | 2025-01-28 | — | — | CN | claimed |
| CN-111465446-B | Reactive silica-alumina matrix component composition for bottoms cracking catalyst | 巴斯夫公司 | 2024-12-03 | — | — | CN | claimed |
| CN-116377272-B | Smelting and purifying method of Mg-Li-Zn-Er-Yb alloy for three-dimensional printing | 上海云铸三维科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118406495-B | Double perovskite nano fluorescent powder for enhancing near infrared emission, preparation method thereof and preparation method of LED device | 哈尔滨工业大学 | 2024-10-01 | — | — | CN | claimed |
| US-12104123-B2 | Reactive silica-alumina matrix component compositions for bottoms cracking catalysts | BASF CORPORATION (US) | 2024-10-01 | — | — | US | claimed |
| CN-102179026-A | Fire extinguishing composition generating extinguishant by pyrolysis | SHAANXI J & R FIRE FIGHTING CO | 2011-09-14 | — | — | CN | claimed |
| CN-102146286-A | Tungstate matrix upper conversion white light emitting material and preparation method thereof | UNIV CHINA GEOSCIENCES WUHAN | 2011-08-10 | — | — | CN | claimed |
| CN-101362605-B | Rare-earth nano oxide preparation method | CHANGCHUN APPLIED CHEMISTRY | 2011-05-18 | — | — | CN | claimed |
| CN-101700902-B | Method for manufacturing rare earth fluoride | BAOTOU RUIDA RARE EARTH MATERIAL CO LTD | 2011-05-04 | — | — | CN | claimed |
| CN-101700902-A | Method for manufacturing rare earth fluoride | BAOTOU RUIDA RARE EARTH MATERI | 2010-05-05 | — | — | CN | claimed |
| CN-101362605-A | Rare-earth nano oxide preparation method | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-02-11 | — | — | CN | claimed |
| WO-2005054132-A1 | TAGGED POLYMERIC MATERIALS AND METHODS FOR THEIR PREPARATION | ORICA AUSTRALIA PTY LTD (AU) | 2005-06-16 | — | — | WO | claimed |
| US-6541674-B2 | Electron-withdrawing group present on carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitrites and condensation is carried out in basic medium | RHODIA CHIMIE (FR) | 2003-04-01 | — | — | US | claimed |
| US-5250478-A | Including sintering aid of ytterbium oxide and/or erbium oxide; density; heat conductivity | KYOCERA CORPORATION (JP) | 1993-10-05 | — | — | US | claimed |
| US-4211882-A | OXIDIZING P-TOLUALDEHYDE, CATALYST CONSISTING OF A MANGANESE COMPOUND, A COBALT COMPOUND, A BROMINE COMPOUND, AND A NICKEL, IRON, CHROMIUM, OR LANTHANIDE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529154-B2 | Electrode for electrolysis | EZH2, TPO, PRDM7 | CA4 118/4885CA1 6/4885FAHD1 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.